Qwen2.5 72B VRAM needed and GPU rental cost
Qwen2.5 72B has 72.7 billion parameters (from the model card). Weights alone take 145.4 GB at FP16. With a 20% allowance for the KV cache and activations, plan for about 174 GB of VRAM at FP16, 87 GB at FP8 and 44 GB at INT4. The cheapest public on-demand way to hold it at FP8 is 2x L40S at Massed Compute, $1.94/hr.
- Parameters
- 72.7B
- From the model card
- FP16
- 174 GB
- Estimated VRAM
- FP8
- 87 GB
- Estimated VRAM
- INT4
- 44 GB
- Estimated VRAM
Memory and cost
Estimated VRAM and the cheapest public rental that fits
Each row is a way to run or tune Qwen2.5 72B. The option is the cheapest on-demand price we track, from rows we rate high or medium confidence, on one node of up to 8 GPUs. Change the precision or hours in the calculator.
| Mode | Estimated VRAM | Cheapest public on-demand option | Per month (730 h) | Source |
|---|---|---|---|---|
| Inference, FP16 or BF16 | 174 GB | 3x A100 at Thunder Compute, $3.27 per hour | $2,387.10 | Source |
| Inference, FP8 or INT8 | 87 GB | 2x L40S at Massed Compute, $1.94 per hour | $1,416.20 | Source |
| Inference, INT4 (4-bit) | 44 GB | 1x L40S at Massed Compute, $0.97 per hour | $708.10 | Source |
| Fine-tune, LoRA (16-bit base) | 174 GB | 3x A100 at Thunder Compute, $3.27 per hour | $2,387.10 | Source |
| Fine-tune, QLoRA (4-bit base) | 44 GB | 1x L40S at Massed Compute, $0.97 per hour | $708.10 | Source |
| Fine-tune, full (Adam, mixed precision) | 1396 GB | 8x MI300X at Crusoe, $27.60 per hour | $20,148.00 | Source |
Fit by chip
How many GPUs Qwen2.5 72B needs, by chip
Number of GPUs whose combined memory covers the estimate. Compare the chips on their price pages.
| Precision | L40S 48 GB | A100 80 GB | H100 80 GB | H200 141 GB | B200 180 GB | MI300X 192 GB | B300 288 GB |
|---|---|---|---|---|---|---|---|
| FP16 (174 GB) | 4 | 3 | 3 | 2 | 1 | 1 | 1 |
| FP8 (87 GB) | 2 | 2 | 2 | 1 | 1 | 1 | 1 |
| INT4 (44 GB) | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
FAQ
Qwen2.5 72B questions
How much VRAM does Qwen2.5 72B need?
About 174 GB at FP16, 87 GB at FP8 and 44 GB at INT4. These are estimates: parameters times bytes per parameter, plus 20% for the KV cache and activations. Long contexts and large batches need more.
Can Qwen2.5 72B run on one H100?
An H100 has 80 GB. At FP16 it needs 3 H100 GPUs, at FP8 2 and at INT4 1, by this estimate.
What does it cost to rent a GPU for Qwen2.5 72B?
At FP8 the cheapest public on-demand option we track is 2x L40S at Massed Compute, $1.94/hr, about $1,416.20 for a 730-hour month. At INT4 it is 1x L40S at Massed Compute, $0.97/hr. Prices change often, so check the source link on each row. Last checked Nov 9, 2026.
How are these estimates made?
Memory is the parameter count times bytes per parameter (2 for FP16, 1 for FP8, 0.5 for INT4), times 1.2. Fine-tuning uses 2 bytes for LoRA, 0.5 for QLoRA and 16 for full fine-tuning with Adam (2 weights, 2 gradients, 12 optimizer bytes), times 1.2. Real usage depends on the framework, context length and batch size.
Need this capacity?
Tell us the GPU, count, term, region and budget. We reply with the public prices that match and the checks to run before you pay. Free, and we do not sell compute.